Life Extension Laboratories: 1 | 2
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Measurements and Laboratory Work for Life Extension Applications
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Anti-Aging Medicine 1
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Hyperlinked reference study notes on the Molecular Biology of Aging
[Links,
Books,
Papers,
Links/ref,
Books/ref,
Papers/ref]
| Mechanisms of Aging
| Innovita
|[ Wikipedia
| Wikigenes
| iHOP
| SA Biosciences
]| Geron
A,
A',
A'',
B
| TA Sciences
| Sierra Sciences
| Maximum Telomere Support
| RevGenetics
| Terraternal
Search:
Journals
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Highlight Links
Telomere Measurements
Telomerase Expression Measurements
Telomere Articles and Links
Cancer and the Gene
Measuring Cellular Senescence
Clinical Testing
Academic Laboratories and Programs
Symposia and Conferences in Anti-Aging Medicine
[Links]
Laboratory Equipment & Material Vendors
Laboratory Topic Reference Links
Medical Schools and Exams
Histology
Software
Cell Culturing
Telomere Measurements [Links, Books, Papers] (See [81s] on small-molecule telomerase activators for lengthening telomeres.)
Shay/Wright Laboratory Methods
Biowww.net/telomere and telomerase assays.
Therapy and diagnosis of conditions related to telomere length and/or telomerase activity Michael D. West, WE Wright, J.Shay, with many useful refs.
Assessment of Telomere Length [Books] and factors that contribute to telomere stability [Books]
Telomere Length Measurements using Fluorescence Microscopy (PhD thesis) [Books]
Telomere Length Measurements Using Digital Fluorescence Microscopy
Telomere Length Measurements in Leukocyte Subsets via Multi-Colored Flow-Fish [Books/in Leukocytes]
Telomere Length Analysis with Multi-Color Flow-FISH
[Books, Amazon, Papers, Patents, at Repeat Diagnostics, Wiki/Flow FISH]
Telomere Length Analysis via T/C-Fish (telomere/centromere-FISH) [Links, Papers, Amazon; Links/telomere-centromere FISH].
Quantitative Fluorescence In Situ Hybridization (Q-FISH) [Links, Books, Papers, Patents, Amazon]
Telomere Analysis with Metasystems Telomere Analysis Software [Books/Telomere Analysis Software]
Lansdorp Lab: Telomere Measurement Software (TFL-Telo)
Quantitative FISH image analysis [Books] (try Google & Adir)
Telomere Length Measurement via FISH & Flow Cytometry [Books]
Karyotype & Spectral Karyotype with Fluorescent In Situ Hybridization (FISH) [Books]
Telomere Length Measurement by Fluorescent In Situ Hybridization & Flow Cytometry: Tips & Pitfalls
Telomere Length Measurement with Q-Fish | TeloQuant Telomere Length Measurement Kit [Books]
Telomere Length Measurement in Blood Granulocytes [Links, Books, Papers; TA Sciences, Greta Blackburn Letter on 460 bp/year using Patton Protocol].
Telomere Length Measurement Links || Google
TRAP - Telomerase Repeat Amplification Protocol (Links) [Books, Papers], TRAP kits [Links, Books, Papers]
Richard M. Cawthon, Telomere length measurement by a novel monochrome multiplex quantitative PCR method, Nucleic Acids Res. 2009 February; 37(3).
See Biotechniques.com/A
quantitative real-time PCR method for absolute telomere length for a Cawthon-method implementation.
See also Marcel E. Gil and Thérèsa L. Coetzer, (2004)
Real-time quantitative PCR of telomere length,
Molecular Biotechnology, Volume 27, Number 2, June, 2004 for another Cawthon implementation
using a Roche LightCycler.
Immununohistochemical Staining [Books, Wikipedia]
Invitrogen Molecular Probes
[Books]
| Invitrogen Handbook
| NIH: Innovation in Molecular Probes
Fluorescent Probes [Books]
Telomere Shortening and Senescence in Rat Brains [Books], telomeres and rat brains
Fluorescence Microscopes
[Books]
| Digital Cameras and Image-Processing Software for Microscopy [Books]
Robbins Scientific
| Laboratory Automation Companies [Books]
Electron Microscopy in DNA sequence measurements [Books]
Five methods for measuring the length of telomere repeats have been described:
(1) Telomere measurement by quantitative PCR
[Books].
See also Telomere length measured at
nucleotide resolution by gene sequencing after telomere PCR
[Links,
Papers].
See Marcel E. Gil1 and Theresa L. Coetzer, 2004: Real-time quantitative PCR of telomere length, Molecular Biotechnology, Humana Press Inc.
Issue Vol 27, No. 2, June, 2004. See also Richard M. Cawthon, 2002: Telomere measurement by quantitative PCR, Nucleic Acids Research, 2002, Vol. 30, No. 10 e47, Oxford University Press.
Nanopore DNA Sequencing [Links]
may be used on telomeres in the future.
See Next_Big_Future/Nanopore Sequencing.
(2) Southern
blot analysis of telomere restriction fragments.
[Books,
Papers]
(3) Quantitative
fluorescence in situ hybridization with digital fluorescence microscopy (Q-FISH).
See Chromosome Preparation for telomere FISH. (About 200 bp resolution.)
[Links,
Books].
(4) Quantitative fluorescence in situ hybridization with flow cytometry (flow-FISH).
____[Books,
Papers]
(5) Quantitative fluorescent in situ hybridization laser scanning cytometry (Q-FISHLSC) using a fluorescent-labeled peptide nucleic acid probe. For laser scanning cytometry for measuring fluorescent signals from LSC, see CompuCyte, Cambridge, Mass. [Books/Q-FISHLSC, Papers]
See [Books/telomere measurement, Books/telomere length assessment, NCBI Papers].
[Books/Telomeres and Telomerase: Methods and Protocols, Links, Papers].
See Links/restriction endonucleases for telomere length research and Books/Endonucleases.
Links/restriction endonuclease sources. See New England Biolabs
Books/human sub-telomeric sequences [Links].
Google/Telomere Kits, Roche Telomere Length Assay Kit | Google/Telomere Length Kits | Google/Telomere Protocols
TeloQuant Telomere Length Kit
Repeat Diagnostics [See How Long are My Telomeres article from RevGenetics, mfg Astragaloside IV.] < $700 per measurement.
Telomerase Expression Measurements - TRAP - Telomerase Repeat Amplification Protocol (Links) [Books, Papers], TRAP kits [Links, Books, Papers]. TRAP is "the gold standard" in telomerase activation measurements, "but requires fresh or snap frozen samples for enzyme preservation. Alternative measures include RT-PCR for hRT and for hTERT mRNA." See also [Books/Telomerase Expression Measurements, Links, Links/Telomerase Measurements, Books/Telomerase Measurements].
[Books/Telomeres and Telomerase: Methods and Protocols, Links, Papers].
Allied Biotech, Inc. - Telomerase Detection Kits [Links, Books]
Telomerase enzyme activity [Books] requires expression of two genes [Links/GenBank],
hTRT [Books], the protein catalytic component gene, and
hTR [Books], the telomerase RNA component. [Books/measuring telomerase enzyme activity, Books/measuring telomerase activation, Links/telomerase-associated gene sequences].
See Telomerase-associated gene expression measurements via Northern Blot analysis
____[Links, Papers, (Links/Northern Blot analysis, Books)].
Telomerase-associated gene expression measurements via nuclease protection assays
____[Links, Papers, (Links/nuclease protection assays, Books, Papers)]
Telomerase component gene expression measurement via RT-PCR ISH
____[Links, Papers, (Links/RT-PCR ISH, Books, Papers)]
Quantitative Telomerase Detection Kit, US Biomax, Inc.
MILLIPORE TRAPEZE telomerase detection kit.
Google/Telomerase Kits | Google/Telomerase Protocols
|
Telomere Articles & Links
The end sections of chromosomes (first described in 1888 by Waldeyer) were christened "telomeres" in 1938 by Herman Muller.
Hayflick and Moorehead published The Serial Cultivation of human diploid cell strains in 1961. [Review.]
The discovery of the telomere in Tetrahymena: Blackburn EH, Gall JG (1978).
A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena. J Mol Biol. 1978 Mar 25;120(1):33-53.
Telomerase was first discovered in the ciliate Tetrahymena in 1985 by Greider and Blackburn [Papers]. See Greider [Papers].
The TTAGGG or "T-TAG-GG" sequence in human chromosomes was first described in 1988 [Papers].
Reversible Cellular Senescence: implications for immortalization of normal human diploid fibroblasts.
was first published by Wright and Shay in 1989.
CD Harley, Futcher, and Greider published Telomeres shorten during aging of human fibroblasts in 1990 in Nature 345: 458-460.
Then Extension of life-span by introduction of telomerase into normal human cells was published in 1998. [Papers, Books]
Griffith, Comeau, and Rosenfield published Mammalian Telomeres end in a Large Duplex Loop in 1999, in Cell 97: 503-514.
Calvin B. Harley, et. al., Compositions and Methods for Increasing Telomerase Activity, 2005. (Geron patent ap.)[Papers, Links]
TelDB: Telomere Resources The NIH telomere information center. [Books, Links/telomeres]
Wikipedia on Telomeres
| Telomere
| Infoaging: Telomeres
Telomeres, Telomerase, and Cancer
(A History)
Mapping and Initial Analysis of Human Subtelomeric Sequence Assemblies [Books]
t-loops at trypanosome telomeres [Books]
| t-loops at trypanosome telomeres (2)
T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang
[Books]
Telomeres Do D-Loop�T-Loop Minireview. New insights: Lariat structure in telomeres. [Books]
Bidirectional replication from an internal ori site of the linear N15 plasmid prophage
Synthetic Telomeres & Electron Microscopy of Euplotes Telomerase [Books/Synthetic Telomeres]
How the balance between cells living longer and telomere health is kept without promoting the occurrence of malignancies.
The Mechanism of Telomere Synthesis by Telomerase [Books]
Developmentally regulated initiation of DNA synthesis by telomerase: evidence for factor-assisted de novo telomere formation with links to other articles.
Telomere Synthesis
| Lengthening Telomeres without Telomerase [Books]
Telomerase
[Books]
| Telomerase at Davidson
Cancer and the Gene
Stabilizing G-quadruplex DNA - A New Cancer Cure?
[Books]
| Telomeres, Telomerase, and Cancer
(A History) [Books]
Measuring Cellular Senescence
Testing for Cell Senescence [Books]
| Cell Senescence Assay Kits [Books]
| Cell Biolabs, Inc.
| Cell Biolabs/Senescence
Detecting senescent cells with a stain sensitive to beta-galactosidase | Cellular Senescence and Senescence Biomarkers
Senescence-associated β-galactosidase is lysosomal β-galactosidase
Bo Yun Jung A. Han, et al., Ageing Cell 5(2), 187�195.
Books/detecting senescent cells | Google/Cell Senescence Kits | Google/Cell Senescence Protocols
p16INK4a is a senescence marker measurable with flow cytometry. [Books, Links, article]
Measuring Free Radicals, Free Radical Damage, and Oxidative Stress
Oxidative Stress
[Books/Testing for Oxidative Stress]
| Free Radical Theory of Aging
Measuring free radicals in vivo [Books]
Wiley: Measuring in vivo Oxidative Damage: A Practical Approach [Books]
Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?
[Books/measuring oxidative damage in vivo] | [Books/measuring oxidative damage in vitro]
Malondialdehyde Assay for Lipid Peroxidation
| Cell Biolabs Oxidative Stress Test Assays
AMS Biotechnology Oxidative Stress Assays
| Google/Oxidative Stress Kits | Google/Oxidative Stress Protocols
F2-isoprostane test for oxidative burden, $10.00 - Uses urine dipsticks you purchase and read at home. The
F2-isoprostanes are prostaglandin-like compounds that are specific stable products of fatty acid oxidation
(formed from oxidized arachidonic acid, a major membrane fatty acid) that are reduced by treatment with antioxidants.
|
Measuring DNA Repair Capacity [Books, Links, Papers, LifeExtension]
Serum thiol test [Links] for DNA repair capacity, $65.00 - Draw blood or prick finger and send the test kit to
a commercial lab for analysis. When oxidative stress is high, thiol bonds located within DNA folds of DNA
repair enzymes are degraded by oxidation, so that the enzyme cannot repair your genes. "The thiol status
of serum proteins and DNA repair enzymes has been associated with longevity in many species of mammals." - from The Anti-Aging Solution by Giampapa, Pero, and Zimmerman. In one study,
treatment with CAEs (cat's claw extract) was shown to reverse aging, as indicated by an increase in serum thiols.
AMS Biotechnology DNA Repair & DNA Damage Assays
| Google/DNA Repair Assays
Google/DNA Repair Kits | Google/DNA Repair Protocols
|
Measuring Glycation
Links/Testing Glycation [Books, Papers, LifeExtension]
Google/glycation kits
| Google Books/cellular glycation protocols
Measuring Hormone Levels [Books, Links, Papers, LifeExtension]
Hormone Measurements from saliva for hormonal assessment of endocrine status, $25.00 per panel, test kit costs $10.00 (refundable
with submission of a test panel),
$30.00 for a single test. Collected at home and sent to
a commercial lab. "Analysis determines the free and active hormones that reflect the free and unbound
fraction in serum." One selects two panels. There are 2 for men and 2 for women, an anti-aging panel, and
a competitive athlete panel. The anti-aging panel covers testosterone, cortisol, IgA, DHEA-S, Aldosterone,
Thyroid T3, Thyroid T4, and melatonin.
Google/Hormone Kits
| Google Books/Hormone Protocols
|
Measuring Lipofuscin
Books/detecting lipofuscin
| Books/detecting ceroid
Clinical Testing | [Links/Clinical Testing Directories] Biocompare
|| Biowww.net
|| Clinician InfoRetriever
|| IndexAB/Bioinformatics
| IndexPR/Protocols
BioMarkers of Aging by Jennifer Krup, M.D. [Books]
Biomarkers of Aging, Ben Best.
| Inner Age Biomarker Testing
Biomarkers of Longevity at Longevity Institute International. [Books]
Blood Screening [Books]
Blood Testing by the Life Extension Foundation [Books/Blood Testing, Books/Blood Testing in Anti-Aging Medicine]
Blood Granulocytes: Telomere Length Measurement [Links, Books, Papers; TA Sciences, Greta Blackburn Letter on 460 bp/year using Patton Protocol].
Clinical Chemistry (Books), Applied Clinical Chemistry (Books).
Clinical Testing [Books/Clinical Testing]
C-reactive protein testing, inflammation marker [Books].
Diagnosis Links [Books/Medical Diagnosis]
FISH Telomere
Measurement Technique on a Metaphase Spread [Images,
Papers,
Books].
Fluorescent In Situ Hybridization (FISH)
[Wikipedia,
Books,
Amazon;
IndexEH/Gene,
IndexAB/Bioinformatics].
Fluorescent
In Situ Hybridization technique for measurement of telomere length
[Images,
Books,
Amazon;
Wikipedia/Telomeres,
Images].
General Analytical Services Laboratories
Hematology [Wikipedia, Links, Books, Amazon]
Histology [Wikipedia, Links, Books, Amazon].
Homocysteine Testing [Books] measures methylation effectiveness, toxic homocysteine levels
Hormone Test Kit
[Books]
Med Lab Tests online
Medical and Laboratory Sites
| Lab Technologist.com - Breaking News on Lab Equipment [Books/Medical Laboratory Equipment]
MedicineNet Procedures and Tests
Metaphase Spread
[Images,
Books,
Amazon;
Wikipedia/Cytogenetics;
Links/Metaphase Spread Kits,
Images].
Molecular Diagnostics [Books, Amazon].
Nutrition Bioanalysis Tests Testing Kits for Hair Mineral, Cholesterol, Blood Lipids, and Antioxidants. [Books]
Nutritional Ingredients, Analytical Lab [Books]
Pathology [Wikipedia, Links, Books, Amazon]
Private MD Lab Testing Online [Links/medical tests, Books/medical tests, Links/medical diagnostics]
Roche - Cell Biology, Molecular Biology, Gene Expression, Disease & Drug
SA Biosciences
[Links/Pathway Analysis,
Books;
Links/Gene Chips,
Links/Transcripomics,
Links/Systems biology].
Academic Laboratories & Programs [Books/Academic Laboratories | ARC - Aging Research Center]
American Aging Association
Aarhus University, Denmark, Suresh Rattan See the series The Biology of Aging and Its Modulation
Albert Einstein College of Medicine - Longevity Genes Project - Paul Beeson Institute - Dr. Nir Barzilai.
American Federation for Aging Research/Med Student Programs [Home, InfoAging.org]
The Artandi Lab at Stanford University. [Article]
Austad Lab: Dr Stephen N. Austad
Baylor College of Medicine, Huffington Center on Aging
Blackburn Laboratory at the Univ. of Cal. at San Francisco. 2006 Lasker Foundation Award to Elizabeth Blackburn & Carol Greider for telomerase.
Brandeis University Lifespan Lab Links
The Buck Institute for Age Research
Campisi Lab, Ernst Orlando Lawrence Berkeley National Laboratory
The Cech Lab of the Howard Hughes Medical Institute of the Univ. of Colorado at Boulder.
Danish Center for Molecular Gerontology [Books/Molecular Gerontology, Dr. Suresh Rattan]
Ellison Medical Foundation/Telomeres [Home, Replicative Senescence]
Harrington Lab - Telomeres and Telomerase - University of Toronto.
Harvard Molecular Technology and Computational Genetics Labs [Books/Molecular Technology, Books/Computational Genetics]
...Molecular and Cellular Biology at Harvard, with Links || New Harvard Medical School Anti-Aging Medicine Research Center
Henry Wellcome Biogerontology Labs, UK. [Books/Biogerontology]
Huffington Center on Aging, Baylor College of Medicine
Institute for Aging and Health - includes the Henry Wellcome Biogerontology Labs, UK. [Books/Biogerontology]
Institute of Molecular Gerontology/NIH/GOV
International Center for Genetic Engineering and Biotechnology
Karlseder Lab - Molecular and Cell Biology Laboratory Salk Institute for Biological Studies
Laboratory of Experimental Gerontology - Dr. Ingram, senior investigator, American Aging Association
Marine Biological Laboratories/Course: Molecular Biology of Aging with Caleb E. Finch.
Molecular Gerontology, Schools of
Mount Sinai Neurobiology of Aging Laboratories.
National Institute on Aging NIH/NIA.
National Institute of Aging from NIH, Resources
Oakridge National Laboratory - Telomere Quantification by Florescence In Situ Hybridization - Software.
Shay/Wright Laboratory at the University of Texas Medical Center - Optical Imaging Core.
Simon Fraser University, Canada Gerontology Progams and Research Centers Links.
St. Petersburg Institute of
Bioregulation and Gerontology [Home Page, About Us, Links/Schools of Bioregulation and Gerontology]
Szostak Labs- Jack W. Szostak - Lasker Award with Greider and Blackburn. [Article with photo]
UCLA Molecular Genetics Links
University of Aarhus, Denmark, Suresh Rattan See the series The Biology of Aging and Its Modulation
University of Arkansas - Deptartment of Geriatrics
University of Chicago: Clinical Services - Telomere Analysis, FISH probes.
University of Groningen (Netherlands)
University of Idaho - Austad Lab, - Dr. Holmes
University of Michigan Institute of Gerontology
University of North Carolina at Chapel Hill, Department of Biochemistry and Biophysics
USC Davis School of Gerontology, Caleb E. Finch [The Biology of Human Longevity].
University of Washington - Basic Biology of Aging, Healthy Aging Research Network
Univeristy of Wisconsin - Judd Aiken - Role of mitochondria in aging.
US Schools of Molecular Biology [Links]
VCU Biochemistry
Wayne State University - Institute of Gerontology - Robert Arking [Biology of Aging: Observations and Principles].
West Virginia University Center on Aging Links || Penn State Gerontology Links
WISTAR Institute: Novel Telomerase Activators [Links] have been proposed in Israel at the WISTAR Institute
____based on the design of molecules to regulate telomerase. See WISTAR professor
____Emmanuel Skordalakes PhD [Links, Papers, Images].
Who's Who in Gerontology
___Judd Aiken, Bruce Ames [Links, University of California],
___Robert Arking [Biology of Aging: Observations and Principles], Steven N. Austad [Amazon],
___Gustavo Barja [Books, Amazon], Andrzej Bartke [Message, Links], Dr. Nir Barzilai, M.D. [Beeson Institute/Dr. Nir Barzilai]
___Seymour Benzer [Caltech Lab, Books], Ben Best [Links],
___Elizabeth Blackburn [Blackburn Lab, Links, Books, Images, Amazon, Papers, Patents],
___Maria A. Blasco [Links, Papers], Vilhelm A. Bohr [National Institute on Aging, Links, Books]....
Symposia and Conferences in Anti-Aging Medicine
[Links]
The Tenth International Symposium
on Neurobiology and Neuroendocrinology of Aging, July 25–30, 2010, Bregenz, Austria.
Vendors | Biocompare
| Biotech-Web
| LabEquip
| Links/biotech lab equip
| Links/medical lab equip
| Biowww.net
|| Google
| Yahoo
454 Life Sciences - Rapid DNA sequencing [Links, Wikipedia/DNA Sequencing]
Abbott Laboratories/VYSIS, Abbott Molecular Inc.
Active Motif - Tools to analyze and measure [Links, Books] functions in the cell nucleus [Books, Links].
addgene (plasmids), addgene/hTERT.
Advanced Cell Technology - Embryonic stem cell technology.
Agilent Technologies - Life Science Lab Products, and electronic.
AI Imaging A Genetix Company - Includes products for FISH analysis.
Allied Biotech, Inc. - Telomerase Detection Kits [Links, Books]
Altogen Polymer-, lipid-, and nanoparticle-based transfection technologies.
Ambion The RNA company [Products, Links]
Amplicon Express - DNA sequencing [Books] and other bioservices, cloning and expression vectors, ect. [Books]
AMS Biotechnology - Research products for genomics, proteomics and immunology, including assay kits, cDNA, RNA, microarrays, western blots, polyclonal antibodies, monoclonal antibodies, antigens & ELISA kits.
Antagene Custom Antibody & Peptide Synthesis - Peptide synthesis service.
Aphelion Imaging software toolkits useful in telomere FISH work.
Amersham Biosciences, GE Healthcare Products, [Amersham RNA labeling kit], [Amersham Pharmacia Biotech, Restriction Enzymes]
AMGEN - Protein therapeutics.
Analytical Lab - Nutritional Ingredients
Applied Biosystems - Gene Sequencing apparatus [Books] & Telomere Extension by Telomerase Pathway Atlas
___ GeneAssist Pathway Atlas - The molecular biology of the cell: "signal transduction, metabolic and disease state pathway maps, as well as their descriptions and relevant references. When a protein is selected from one of the maps, a detailed view appears showing additional gene information along with the recommended Silencer� siRNAs and corresponding TaqMan� Gene Expression Assays for studying that particular gene."
|
Applied Imaging [Links] Cytovision
ATCC - American Type Culture Collection - Cell lines for testing, such as telomerase activation testing.
ATCC Bioproducts - Cell Immortalization via hTERT plasmids - Immortalization of Cells in Culture. [Books] || Serotec Antibodies.
Beckman Coulter, Inc. - Diagnostics, Biomedical Research Applications.
BD - Becton, Dickinson, and Company [Products], manufacturer of Vacutainers for phlebotomy, syringes; mouse collagen for coatings; flow cytometry, ect.
Biocarta PATHWAYS: Telomeres, Telomerase, and Immortality.
Blue Heron Biotechnology - Synthesize genes and synthetic DNA sequences economically and with perfect accuracy with
Blue Heron Bio's GeneMaker� proprietary, novel and high throughput design and synthesis platform.
Brinkman Instruments - Bio & Analytical Chemistry lab equipment.
Biolab equipment, advanced [Books], Polymerase Chain Reaction kits, ect. [Books]
BIOMOL on-line catalog.
Biopsy Equipment [Links/biopsy equipment, Links/fine needle aspiration biopsy equipment]
Bioanalytical Systems
Bio-Rad Laboratories - Life Science Research, Clinical Diagnostics, Informatics, Separations, Ed.
Biotechnology Links [Books], Biotechnology Equipment links [Books]
Bristol-Myers Squibb - Medicines, medical imaging.
Bruker X-ray diffraction apparatus for x-ray diffraction determination of structure
[Books/apparatus, Books/structure]
Caliper Life Sciences - Products by application - Drug Discovery, Drug Development, Genomics, Proteomics.
CRi - Cambridge Research & Instrumentation - "Oosight" system for nuclear transfer cloning, recently used to clone monkeys.
CamScan Scanning Electron Microscopes [Books]
Cambrex - Pharmaceutical and Bioscience Products - About Cambrex
Carolina Biological Supply Company Materials to support DNA Science, Dolan DNA Learning Center of the Cold Spring Harbor Laboratory.
Cascade Biologics - Human cell cultures, for telomerase activation testing, for instance.
Cell Biolabs - Oxidative Stess Assays, similar Assays for Science Research
Cell Culturing Equipment (Google Links) [Books/Cell Culturing, Amazon/cell culturing]
Cell Culturing Technologies [Books]
Cell-Sorting [Books, Amazon].
Cell-Sorting Machine Vendors
[links,
Books, Papers] |
Cell-Sorting & Mitochondrial Aging
Centrifuges [Books]
Chemical Laboratory Supplies Net
Chromatography
[Books]
| High Performance Liquid chromatography [Books]
| Affinity Chromatography
[Books]
Clinical Chemistry Equipment (Google Links)
Cryostats [Books], Cryosection Technique [Books], Cryosection Protocol
Daiichi Pure Chemicals - Life Science Products.
DNA 2.0 - Synthetic Genes, Gene Design Software.[Books/Gene Design, Links]
Epicentre Biotechnologies (Products)
EMD Biosciences: Calbiochem, Novabiochem, Novagen: Products for:
Protein Phosphorylation/Dephosphorylation, Cell Cycle & Apoptosis, Drug Discovery,
Proteomics, Calcium Signaling, Nitric Oxide & Oxidative Stress,
Cell Adhesion & Extracellular Matrix, G-proteins, Proteases, Lipid Signaling, Neurobiology, Cytokines & Growth Factors.
Eppendorf products: Cell Manipulation, Centrifugation, Lab Automation, Microarrays, PCR, ect.
European Collection of Cell Cultures - ECACC
Faster Cures - The Center for Accelerating Medical Solutions
Fisher Scientific: Life Science, Food Diagnostics, Chemicals, Organics, Science Ed., Healthcare, ect.
Fluorescence Microscopes
[Books]
| Digital Cameras and Image-Processing Software for Microscopy [Books]
Garden State Nutritionals - Packages TA-65 into capsules for TA Sciences, tests new drugs.
GE Healthcare Products.
Gel Electrophoresis [Books],
SDS Gel Electrophoresis [Books, History & Methods],
Genentech - Leading provider of anti-tumor therapeutics in the United States, biotechnology.
Genscript - Gene, Peptide, Protein, and Antibody Services. Could synthesize Epithalon Peptide, for instance. Protein product pipeline available.
genzyme - Protein and antibody therapies, polymers and small molecule therapies, cell and gene therapies, and biomaterials.
Geron [Wikipedia, Links] - Telomere & telomerase technologies. [patents, European patent/telomerase activation methods, European patent/Astralagus extracts(for Hong Kong U.)]
Glassware, Scientific and Laboratory
[Books]
|| Surplus Lab
|| Best Lab Deals
Global Scientific Supply - General Biolab and Chemlab equipment.
GMI - Lab Instrumentation (many brands)
Greyfield Optical Inc. Online Videos, microscopy equipment.
Grizzly Analytical
Hach Co..
Hammamatsu Photonics - Hammamatsu Ora Camera - used in Shay/Wright Telomere/Centromere FISH.
Henogen - Biomanufacturing and pharmaceuticals. Acquired 4C Biotech, a source of human cell cultures.
HGS - Human Genome Sciences - Biopharmaceuticals, including drugs to treat hepatitis C, lupus, anthrax disease, cancer, rheumatoid arthritis and HIV/AIDS.
IDT - Integrated DNA Technologies (catalog), Custom gene synthesis, IDT SciTools.
Illumina Gene Expression Product Portfolio - [Links/whole genome bead array technology, Books, Papers]
Imgenex [Products] - Innovations in functional genomics.
Immunohistochemical staining kits [Books]
InPhotonics, Inc. - Raman spectroscopy.
Invitrogen | Invitrogen Products
| Focus Areas
| Kinase Biology
| Human Biological Pathways
Kaiser Optical Systems, Inc. - Raman Spectroscopy.
Leeman Labs (Teledyne) - Atomic spectroscopy.
Lifescan, Inc. - Glucose monitoring.
LightCycler Systems for Real-time PCR from Roche Applied Science
Lilly - Eli Lilly & Co., biopharmaceuticals, R&D.
Marlingen Biosciences [Products] - Multiple transcription factor identification, mitochondrial DNA assays, ect.
MCLAB advanced bioservices and products- with free on-line software tools.
McKinley Scientific Laboratory Supplies [Books]
Medical Equipment Links & related | Medical Device Resource Center
| Medical Equipment (Google Links)
Medical Laboratory Equipment (Google Links)
Merck
Mettler Toledo, Inc. Lab Equipment.
Microbiology Equipment (Google Links)
Microcentrifuges [Books, Links]
MicroPhotonics X-Ray Diffrac.
Microtomes [Wikipedia, Books], Ultramicrotome [Links, Books]
MILLIPORE - Tools and services for bioscience research and biopharmaceutical manufacturing. TRAPEZE telomerase detection kit.
Molecular Dynamics Phosphorimager, ImageQuaNT Workstation
Molecular Probes (Invitrogen)
Mouse and Hamster Racks
[Books/Mouse and Hamster Lab Procedures]
National Instruments.
NIH Image Processing software - used in FISH telomere studies. [Links, Books].
Nikkon Microscopy (Nikkon USA) - Microscopy U. - Microscopy Tutorials, Image Galleries, Fluorescence Microscopy, ect.
Ocean Optics - Optical sensing and spectroscopy.
Pall Corporation - Laboratory Products - Filtration, Separation & Purification.
PCR amplification kits [Books, Links, Fast PCR Tutorial]
PDL BioPharma - IV Busulfex to support allogeneic hematopoietic stem cell transplantation, biopharamaceuticals.
Peptide Synthesis, Custom
[Books, Papers], Peptide Synthesis [Wikipedia, Books], Peptide Sythesizers [Books, Suppliers]
Perkin-Elmer Life and Analytical Sciences - High Throughput Screening [Links, Wikipedia, Books, Amazon].
Pfizer - Pharmaceuticals and pharmaceutical research.
Pharmacological Lab Equipment Suppliers [Books]
Phoenix Biomolecular - Telomerase activation therapies.
Postnova Analytics - Advanced analytical products.
Promega Automated analysis systems, Cellular Analysis, DNA & RNA analysis, Drug Discovery, Genetic Identity, Molecular Diagnostics.
Proquinase Tools and Testing.
ProSpec Protein Specialists - Provide some exotic telomerase activators, such as Interleukin-2, EGF, and PDGF.
QIAGEN Sample and assay technologies for biomedical and drug development, ect, [Links/Molecular Diagnostics].
Rainin Instruments Pipetting Solutions
Repeat Diagnostics [See How Long are My Telomeres article from RevGenetics, mfg Astragaloside IV.]
Robbins Scientific
| Laboratory Automation Companies [Books]
Roche - Cell Biology, Molecular Biology, Gene Expression, Disease & Drug Research
[Books/Cell Biology,
Books/Molecular Biology,
Books/Gene Expression,
Books/Disease Research,
Books/Drug Research].
SA Biosciences
[Links/Pathway Analysis,
Books;
Links/Gene Chips,
Links/Transcripomics,
Links/Systems biology].
SDS Gel Electrophoresis [Books],
Gel Electrophoresis [Books].
Serva - Electrophoresis Reagents, Equipment
Sidec - Protein tomography with electron microscopy.
Sierra Sciences [Wikipedia, Links] - Developing medicines and therapies that will reverse the effects of human aging; telomerase activation research.
Sigma Aldrich - Life Science, Analytical/Chromatography, Chemistry, Biochemicals, ect.
Spectro Analytical Instruments
Staining Apparatus for Histology and Light Microscopy [Links, Books/..for microscopy, Books/..for histology]
Stem Cell Culturing Equipment (Google Links)
Sterilization Equipment (Google Links)
Stratagene DNA Extraction Kit used in T/C FISH.
Surgical Equipment (Google Links)
Synthecon 3D Cell Culture Systems [Books]
| Cell Culturing Technologies [Books]
T. A. Instruments - Thermal Analysis Instruments.
TA Sciences [Links] - Telomerase Activation Sciences. - TA-65, probably cycloastragenol, from astragalus extract [Forum].
Telomolecular Nanotechnologies [Links]. Telomerase Activation Techniques and Life Extension Methods.
_____Telomolecular Nanotechnologies Corporate Video.
Thermo Scientific - Biolab equipment.
Trade Shows Eventseye: Trade Shows Worldwide, Links/Trade Shows USA, Biz Trade Shows, TS Event Resource, TS Scratchpad.
Trevigen - Bioscience Test Protocols for Cancer Research; DNA Damage, ect.
US Biomax, Inc. - Quantitative Telomerase Detection Kits, plus Tissue Arrays, Tissue microarrays, Tissue Banks, and Protein microarrays.
Varian - Information Rich Detection, Chromatography, Spectroscopy, Vacuum Technologies.
Vector Laboratories - Immunohistochemical, biomedical labeling & detection systems.
Whatman separation technologies.
Wyeth BioPharma - Development and manufacturing of recombinant protein biopharmaceuticals.
Zeiss Microscopy & Image Analysis [Books, Links, Yahoo Links] - Axioplan 2 Fluorescense Microscope, used by Shay & Wright.
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